Abstract |
In 240 patients with symptoms of dyspepsia, recruited consecutively and investigated in 12 hospitals in Japan, 24.2% were diagnosed having organic dyspepsia; 75.8% had functional dyspepsia, of whom 63.2% were diagnosed by the investigator having dysmotility-like, 13.7% ulcer-like, 11.5% reflux-like, and 11.5% non-specific dyspepsia. There was, however, considerable overlap of symptom profiles. Cisapride therapy initiated in functional dyspeptic patients resulted in moderate or marked improvement in 79.1% of the patients with the highest response rates for dysmotility-like (85.2%), reflux-like (81.0%), and non-specific dyspepsia (76.1%) (versus 52.0% for ulcer-like dyspepsia).
|
Authors | M Inoue, T Sekiguchi, S Harasawa, T Miwa, A Miyoshi |
Journal | Scandinavian journal of gastroenterology. Supplement
(Scand J Gastroenterol Suppl)
Vol. 195
Pg. 36-8; discussion 38-9
( 1993)
ISSN: 0085-5928 [Print] England |
PMID | 8516656
(Publication Type: Journal Article, Multicenter Study)
|
Chemical References |
|
Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Child
- Cisapride
- Dyspepsia
(classification, drug therapy, physiopathology)
- Female
- Gastrointestinal Motility
(drug effects)
- Humans
- Japan
- Male
- Middle Aged
- Piperidines
(therapeutic use)
- Treatment Outcome
|