[Interrelationship of changes in central hemodynamics in the postresucitation period with development of posthypoxic cerebral edema].

Abstract

A syndrome of low cardiac output developed between the 1st and the 3rd hours after the resuscitation in 16 dogs after the arrest of blood circulation for 15 minutes. The increase of cardiac output at the initial period of resuscitation took place in 50% of cases before the development of this syndrome. In the absence of hyperperfusion at the beginning of the resuscitation the animals died 9 to 23 hours after the experiment. Cerebral cortex edema developed in all the survived dogs which had low cardiac output 24 hours after resuscitation, but it was not observed in animals with high cardiac output.

• Authors: I S Novoderzhkina, I E Trubina, G K Boliakina, A V Volkov
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 83 Issue 3 Pg. 266-8 (Mar 1977) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Vzaimosviaz' izmeneniĭ tsentral'noĭ gemodinamiki v postreanimatsionnom periode s razvitiem postgipoksicheskogo oteka mozga
• PMID: 851628 (Publication Type: English Abstract, Journal Article)

Topics

• Animals
• Brain Edema (physiopathology)
• Cardiac Output
• Dogs
• Female
• Hemodynamics
• Male
• Resuscitation
• Syndrome
• Vascular Resistance
• Ventricular Fibrillation