[Chemoprophylaxis of ophthalmia neonatorum through vertical infection. Evaluation of Crede's method using norfloxacin and gentamicin].

Abstract

Crede's method was evaluated using norfloxacin (NFLX) and gentamicin (GM) to show the clinical significance of chemoprophylaxis against ophthalmia neonatorum occurring through vertical infections. The obtained results are summarized as follows. 1. NFLX and GM were separately instilled using Crede's original method in 171 cases selected from all cases of delivery encountered in this hospital during a period of 5 months in 1991. The two groups had similar backgrounds. 2. NFLX and GM were effective in 70 of 71 cases and in 96 of 100 cases, respectively. No side effects were found in either groups. 3. From 4 of 5 ineffective cases were isolated staphylococci, which were sensitive to NFLX and GM.

• Authors: K Seiga, T Shoji
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 46 Issue 4 Pg. 331-6 (Apr 1993) ISSN: 0368-2781 [Print] Japan
• PMID: 8515565 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Gentamicins
• Norfloxacin

Topics

• Adult
• Female
• Gentamicins (therapeutic use)
• Humans
• Infant, Newborn
• Norfloxacin (therapeutic use)
• Ophthalmia Neonatorum (drug therapy)
• Pregnancy