[Cystine lithiasis and its treatment with d-penicillamine. The experience in a nephrology service in a 23-year period. Apropos of 26 patients].

Abstract

From 1968 through 1990, 26 patients with cystine lithiasis were followed-up for a mean of 10.6 +/- 6.7 years in the department of Nephrology of the Pellegrin Hospital in Bordeaux, France. Clinical and surgical features in these patients are reported as well as the experience acquired with the use of D-penicillamine over the 23-year study period. Long-term D-penicillamine treatment can be used in patients with cystinuria and is both effective and safe. Use of other thiol compounds for preventing cystine stone formation was not necessary in our patients.

• Authors: C Combe, C Deforges-Lasseur, Z Chehab, V de Précigout, M Aparicio
• Journal: Annales d'urologie (Ann Urol (Paris)) Vol. 27 Issue 2 Pg. 79-83 ( 1993) ISSN: 0003-4401 [Print] France
• Vernacular Title: La lithiase cystinique et son traitement par la d-pénicillamine. Expérience d'un Service de Néphrologie sur une période de vingt-trois ans a propos de vingt-six patients.
• PMID: 8503655 (Publication Type: Journal Article)

Chemical References

• Penicillamine

Topics

• Adolescent
• Adult
• Age Factors
• Child
• Child, Preschool
• Cystinuria (complications, drug therapy)
• Female
• Follow-Up Studies
• Humans
• Infant
• Male
• Middle Aged
• Penicillamine (adverse effects, therapeutic use)
• Sex Characteristics
• Ultrasonography
• Urinary Calculi (chemistry, diagnostic imaging, drug therapy, prevention & control)