Moebius syndrome associated with pituitary dwarfism and hypoplastic optic disc.

Abstract

A 17 year old male patient with Moebius syndrome with pituitary dwarfism and unilateral hypoplastic optic disc is presented. Although there have been several reports of an association of Moebius syndrome and pituitary dysfunction, growth hormone deficiency has not been reported previously. These associations may give some insight into the pathogenesis of Moebius syndrome.

• Authors: N Hashimoto, Y Sakakihara, Y Miki, J Kagawa, S Egi, S Kamoshita
• Journal: Acta paediatrica Japonica : Overseas edition (Acta Paediatr Jpn) Vol. 35 Issue 2 Pg. 144-7 (Apr 1993) ISSN: 0374-5600 [Print] Australia
• PMID: 8503272 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Growth Hormone

Topics

• Adolescent
• Dwarfism, Pituitary (congenital, diagnosis, drug therapy)
• Facial Paralysis (congenital, diagnosis)
• Growth Hormone (therapeutic use)
• Humans
• Male
• Ophthalmoplegia (congenital, diagnosis)
• Syndrome