Abstract |
Lymphangiosarcoma after mastectomy was first described by Stewart and Treves in 1948. Today, this tumor associated with chronic lymphedema has become a rare entity, due to less radical surgery. Chronic lymphedema and lymphangiectasia of limbs preceding lymphangiosarcoma may not only be induced by radical mastectomy. Also post-traumatic, congenital, filarial-associated or spontaneous chronic lymphedema may be associated with lymphangiosarcoma. A time interval of years seems to be required before malignant changes supervene and lymphangiosarcoma develops. This paper describes a case with lethal and arising in an edematous arm years after radical mastectomy and irradiation. Current concepts of etiology, histopathology, immunohistology, diagnostic investigation, treatment and prognosis are presented.
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Authors | I C Kiricuta, J Dämmrich |
Journal | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
(Strahlenther Onkol)
Vol. 169
Issue 5
Pg. 291-5
(May 1993)
ISSN: 0179-7158 [Print] Germany |
PMID | 8503088
(Publication Type: Case Reports, Journal Article)
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Topics |
- Aged
- Arm
- Breast Neoplasms
(surgery)
- Chronic Disease
- Female
- Humans
- Lymphangiosarcoma
(etiology)
- Lymphedema
(etiology)
- Mastectomy, Radical
(adverse effects)
- Time Factors
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