HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Atherectomy of the subclavian artery for patients with symptomatic coronary-subclavian steal syndrome.

AbstractOBJECTIVES:
This study addresses the efficacy of directional atherectomy in the subclavian artery for the relief of angina in patients with the coronary-subclavian steal syndrome. In addition, we review the histologic findings from the atherectomy specimens.
BACKGROUND:
The coronary-subclavian steal syndrome may occur after internal mammary-coronary artery bypass grafting. It is due to a stenosis in the subclavian artery proximal to the origin of the internal mammary artery and causes frank ischemia to the area supplied by the graft. Currently, surgery is the corrective procedure of choice.
METHODS:
In three patients with severe subclavian artery stenoses and unstable angina, directional atherectomy was performed using a peripheral atherectomy catheter through a percutaneous femoral approach. The patients ranged from 43 to 71 years of age and had undergone internal mammary-coronary artery bypass grafting 3 to 10 years previously. Each patient had severe peripheral vascular and cerebrovascular disease.
RESULTS:
All three patients had immediate symptomatic relief after the atherectomy, and postprocedure exercise testing demonstrated improved cardiac function. Two patients remain asymptomatic at 7 and 8 months, respectively; the third patient developed unstable angina 9 months later because of severe restenosis that was again successfully treated with atherectomy. Histologic examination of the specimens revealed atherosclerotic plaque, occasionally with adventitia. The specimen from the repeat atherectomy showed severe intimal hyperplasia.
CONCLUSIONS:
Directional atherectomy appears to be a safe and effective treatment for coronary-subclavian steal syndrome. This procedure may be the treatment of choice for patients in whom a vascular bypass operation is not feasible.
AuthorsJ A Breall, W Grossman, I E Stillman, L E Gianturco, D Kim
JournalJournal of the American College of Cardiology (J Am Coll Cardiol) Vol. 21 Issue 7 Pg. 1564-7 (Jun 1993) ISSN: 0735-1097 [Print] United States
PMID8496520 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)
Topics
  • Adult
  • Aged
  • Angina Pectoris (etiology, surgery)
  • Atherectomy
  • Coronary Disease (surgery)
  • Female
  • Humans
  • Internal Mammary-Coronary Artery Anastomosis
  • Male
  • Middle Aged
  • Postoperative Complications (surgery)
  • Subclavian Artery (surgery)
  • Subclavian Steal Syndrome (surgery)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: