Rheumatoid nodules at the cement-bone interface in revision arthroplasty of rheumatoid patients.

Abstract	We studied the histology of the cement-bone interface and the regenerated synovium in ten aseptically loosened arthroplasties in rheumatoid patients. In two patients we found rheumatoid nodules at the cement-bone interface and marked lymphoplasmacytic infiltration in another three. Failed joints in osteoarthritic patients did not show these changes, and it seems likely that the presence of abundant immunocompetent cells was due to the background disease. We speculate that rheumatoid inflammation contributed to the process of loosening.
Authors	K Inoue, J Nishioka, S Hukuda, K Shichikawa, H Okabe
Journal	The Journal of bone and joint surgery. British volume (J Bone Joint Surg Br) Vol. 75 Issue 3 Pg. 455-8 (May 1993) ISSN: 0301-620X [Print] England
PMID	8496222 (Publication Type: Case Reports, Journal Article)
Chemical References	Bone Cements
Topics	Adult Aged Arthritis, Juvenile (diagnostic imaging, pathology, surgery) Arthritis, Rheumatoid (diagnostic imaging, pathology, surgery) Biopsy Bone Cements Female Hip Prosthesis Humans Knee Prosthesis Male Middle Aged Prosthesis Failure Radiography Reoperation Rheumatoid Nodule (pathology) Synovial Membrane (pathology) Time Factors

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