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Class specific antinuclear antibodies in systemic lupus erythematosus.

AbstractThe incidence and significance of class specific antinuclear antibodies (ANA), specially with relevance to clinical manifestations of arthritis, renal disease and serositis was studied in 40 patients of systemic lupus erythematosus by the indirect immunofluorescent method. Clinical activity was scored by Morimoto's scoring system. A significant correlation was obtained between IgD ANA and clinical activity of the disease and IgG ANA exhibiting lupus pattern of immunofluorescence and serositis.
AuthorsK Savitri, S Sehgal, B N Datta, K S Chugh (Affiliation: Department of Immunopathology, Postgraduate Institute of Medical Education & Research, Chandigarh.)
JournalThe Indian journal of medical research (Indian J Med Res) Vol. 98 Pg. 27-9 (Feb 1993) ISSN: 0971-5916 [Print] INDIA
PMID8495986 (Publication Type: Journal Article)
Chemical References
  • Antibodies, Antinuclear
  • Immunoglobulin D
  • Immunoglobulin G
  • Immunoglobulin M
Topics
  • Antibodies, Antinuclear (analysis)
  • Antibody Specificity
  • Fluorescent Antibody Technique
  • Humans
  • Immunoglobulin D (analysis)
  • Immunoglobulin G (analysis)
  • Immunoglobulin M (analysis)
  • Lupus Erythematosus, Systemic (diagnosis, immunology)
  • Lupus Nephritis (immunology)

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