[The effect of long-term alkali therapy for recurrent calcium stone patients with distal renal tubular acidosis].

Abstract

Alkali therapy is widely accepted as a treatment for recurrent calcium stone patients with distal renal tubular acidosis (dRTA). Nine patients, five with complete and four with incomplete type of dRTA, were treated with alkali agents for more than three years; an average period of 10.8 years. In five patients, new stone formation and stone growth were completely prevented by this treatment. Among the four failed cases, three did not take enough alkali agents (in spite of our medication), and the other had recurrent urinary tract infection resulting in infectious stone formation. In conclusion, the long-term efficacy of alkali therapy for prevention of recurrent stone formation with dRTA is confirmed when the patient takes enough alkali agents and the urinary tract infection is well controlled.

• Authors: S Yamaguchi, T Koide, M Utsunomiya, T Yoshioka, A Okuyama
• Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology (Nihon Hinyokika Gakkai Zasshi) Vol. 84 Issue 4 Pg. 674-9 (Apr 1993) ISSN: 0021-5287 [Print] Japan
• PMID: 8492511 (Publication Type: English Abstract, Journal Article)

Chemical References

• Citrates
• Calcium

Topics

• Acidosis, Renal Tubular (complications)
• Adult
• Calcium (urine)
• Citrates (administration & dosage, therapeutic use)
• Female
• Humans
• Kidney Calculi (complications, drug therapy, urine)
• Kidney Tubules, Distal
• Male
• Middle Aged
• Recurrence