[Isolation and partial characterization of (PAF) platelet-activating-factor].

Abstract

Platelet-activating-factor is a new mediator of anaphylaxis released in numerous mammalian species from basophils and mastocytes by antigens, anti-IgE antiserum, ionophore A 23187, C3a, C5a and neutrophil cationic protein. It is probably a lyso-1-phosphatidylcholine, as evidenced by structural studies isomg phospholipases. It may explain the involvement of platelets in immunopathology.

• Authors: J Benveniste, J Camussi, J M Mencia-Huerta, J Polonsky
• Journal: Annales d'immunologie (Ann Immunol (Paris)) 1977 Jan-Mar Vol. 128 Issue 1-2 Pg. 259-60 ISSN: 0300-4910 [Print] France
• Vernacular Title: Isolement et caractérisation partielle du " platelet-activating-factor " (PAF)
• PMID: 848883 (Publication Type: English Abstract, Journal Article)

Chemical References

• Blood Coagulation Factors

Topics

• Animals
• Basophils
• Blood Coagulation Factors
• Platelet Aggregation
• Swine