Abstract | STUDY OBJECTIVE: DESIGN: Prospective study. SETTING: University-affiliated children's hospital. PATIENTS: Ten former preterm infants, ASA physical status II and III, who were 35 to 49.5 weeks postconceptional age at the time of surgery. INTERVENTIONS: MEASUREMENTS AND MAIN RESULTS: The mean cumulative dose of 2-chloroprocaine was 2.8 +/- 1.0 ml/kg/hr (84 +/- 30 mg/kg/hr) infused over a mean duration of 95 +/- 35 minutes. Serum cholinesterase concentration and plasma 2-chloroprocaine concentration were measured in five infants. CONCLUSIONS:
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Authors | K Henderson, N F Sethna, C B Berde |
Journal | Journal of clinical anesthesia
(J Clin Anesth)
1993 Mar-Apr
Vol. 5
Issue 2
Pg. 129-33
ISSN: 0952-8180 [Print] United States |
PMID | 8476619
(Publication Type: Journal Article)
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Chemical References |
- Anesthetics, Local
- Procaine
- chloroprocaine
- Cholinesterases
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Topics |
- Anesthesia, Caudal
- Anesthetics, Local
(administration & dosage, blood, pharmacology)
- Blood Pressure
(drug effects)
- Cholinesterases
(blood)
- Gestational Age
- Heart Rate
(drug effects)
- Hernia, Inguinal
(surgery)
- Humans
- Infant
- Infant, Newborn
- Infant, Premature
- Procaine
(administration & dosage, analogs & derivatives, blood, pharmacology)
- Prospective Studies
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