Effect of rinsing time on antiplaque-antigingivitis efficacy of listerine.

This double-blind, controlled clinical study compared the effectiveness of 30- and 60-s listerine rinses in both inhibiting the development of, and reducing existing, supragingival plaque and gingivitis, using an experimental gingivitis model. 94 subjects completed this study. For each subject, a modified gingival index, modified Quigley-Hein plaque index and Eastman interdental bleeding index were recorded at baseline and at 2 weeks. Following the baseline examinations, subjects received half-mouth prophylaxes, and began 2 x daily supervised rinsing either with listerine for 30 or 60 s or with a control mouthrinse for 30 s as their sole oral hygiene measure. Statistical analysis (ANCOVA) showed that both the 30- and 60-s listerine rinses were significantly (p < 0.01) more effective than the control in inhibiting and reducing plaque, gingivitis and gingival bleeding. Although 60-s rinses with listerine were significantly more effective (p < 0.01) than 30-s rinses in controlling plaque, the 2 rinse durations were similarly effective in controlling interdental bleeding and gingivitis. This study confirms the recommendation of 2x daily rinsing with listerine for 30 s as an effective regimen for gingivitis control.
AuthorsN M Ross, S M Mankodi, K L Mostler, C H Charles, L L Bartels
JournalJournal of clinical periodontology (J Clin Periodontol) Vol. 20 Issue 4 Pg. 279-81 (Apr 1993) ISSN: 0303-6979 [Print] DENMARK
PMID8473539 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Drug Combinations
  • Mouthwashes
  • Salicylates
  • Terpenes
  • Listerine
  • Adolescent
  • Adult
  • Analysis of Variance
  • Dental Plaque (drug therapy)
  • Dental Plaque Index
  • Double-Blind Method
  • Drug Combinations
  • Female
  • Gingivitis (drug therapy)
  • Humans
  • Male
  • Middle Aged
  • Mouthwashes (administration & dosage, therapeutic use)
  • Oral Hygiene (methods)
  • Periodontal Index
  • Salicylates (administration & dosage, therapeutic use)
  • Terpenes (administration & dosage, therapeutic use)
  • Time Factors

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