Abstract | BACKGROUND: OBSERVATIONS: Nine patients (six males and three females, aged 10 to 47 years) with orofacial granulomatosis were investigated. No evidence of an allergic cause was found using patch or contact urticaria tests. Eating chocolate produced lip swelling in one man, and his lip shrank in size after avoiding this for 12 months. Five patients, aged 10 to 24 years, were treated with high-volume intralesional triamcinolone injections (3 to 10 mL of 10 mg/mL) after first numbing the lips using infraorbital nerve branch and mental nerve block. After 6 weeks, the lip size returned to normal in four patients and was reduced in a fifth. One patient was injected on four occasions over a 2-year period; in four other patients treated once, lip size remained reduced for over 10 months. CONCLUSION:
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Authors | A Sakuntabhai, R I MacLeod, C M Lawrence |
Journal | Archives of dermatology
(Arch Dermatol)
Vol. 129
Issue 4
Pg. 477-80
(Apr 1993)
ISSN: 0003-987X [Print] United States |
PMID | 8466220
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Child
- Female
- Humans
- Injections, Intralesional
(adverse effects)
- Male
- Melkersson-Rosenthal Syndrome
(drug therapy)
- Middle Aged
- Nerve Block
- Pain
(etiology, prevention & control)
- Triamcinolone
(administration & dosage, therapeutic use)
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