Ophthalmic findings in classical galactosaemia--prospective study.

Abstract

Thirty three children with classical galactosaemia diagnosed through newborn screening are considered. It is concluded that cataract formation has a direct relationship with poor dietary control. Erythrocyte galactose-1-phosphate (Gal-1-P) levels do not correspond to cataract formation unless many times higher than normal. The value of crystalline lens biomicroscopy is confirmed as a useful method for monitoring the dietary and biochemical control in classical galactosaemia.

• Authors: B Beigi, M O'Keefe, R Bowell, E Naughten, N Badawi, B Lanigan
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 77 Issue 3 Pg. 162-4 (Mar 1993) ISSN: 0007-1161 [Print] England
• PMID: 8457508 (Publication Type: Journal Article)

Chemical References

• Galactosephosphates
• galactose-1-phosphate

Topics

• Cataract (etiology)
• Child
• Female
• Galactosemias (complications, diet therapy, pathology)
• Galactosephosphates (blood)
• Humans
• Lens, Crystalline (pathology)
• Male
• Patient Compliance
• Prospective Studies