Abstract | BACKGROUND: METHODS: RESULTS: A clear difference was detected between the group receiving folic acid and that receiving vitamin A. In the former group, metaplasia was found in only one rat, atypia was not found, and hyperplasia with marked changes was present in less than 50% of other groups. In the latter group, atypia was found in all of the metaplastic foci. CONCLUSIONS:
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Authors | T Kamei, T Kohno, H Ohwada, Y Takeuchi, Y Hayashi, S Fukuma |
Journal | Cancer
(Cancer)
Vol. 71
Issue 8
Pg. 2477-83
(Apr 15 1993)
ISSN: 0008-543X [Print] United States |
PMID | 8453571
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Vitamin A
- Methylcholanthrene
- Folic Acid
- Vitamin B 12
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Topics |
- Animals
- Body Weight
(drug effects)
- Bronchi
(drug effects, pathology)
- Epithelium
(drug effects, pathology)
- Folic Acid
(blood, pharmacology)
- Hyperplasia
(blood, chemically induced, prevention & control)
- Metaplasia
(blood, chemically induced, prevention & control)
- Methylcholanthrene
- Rats
- Rats, Sprague-Dawley
- Vitamin A
(blood, pharmacology)
- Vitamin B 12
(blood, pharmacology)
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