Activities of acid hydrolases in fibroblasts from normal and cystinotic children.

Abstract	A study of the lysosomal hydrolases bete-galactosidase, beta-glucuronidase, N-acetyl-beta-D-glucosaminidase, and arylsulphatases A and B has been carried out on fibroblasts cultured from seven patients with cystinosis and eight control subjects. beta-Galactosidase activity was found to be consistently lower in cells derived from cystinotics, while the other enzymes studied showed no significant differences between normals and cystinotics.
Authors	K Scardigli, O Koldovsky, M Palmieri, S Segal, B States
Journal	Clinica chimica acta; international journal of clinical chemistry (Clin Chim Acta) Vol. 75 Issue 1 Pg. 13-20 (Feb 15 1977) ISSN: 0009-8981 [Print] Netherlands
PMID	844194 (Publication Type: Comparative Study, Historical Article, Journal Article)
Chemical References	Cystine Hydrolases Arylsulfatases Galactosidases Glycoside Hydrolases
Topics	Arylsulfatases (metabolism) Cells, Cultured Child Cystine (metabolism) Cystinosis (enzymology) Fibroblasts (enzymology) Galactosidases (metabolism) Glycoside Hydrolases (metabolism) History, 18th Century Humans Hydrolases (metabolism) Lysosomes (enzymology) Mitochondria (enzymology)

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