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Ulcerating necrobiosis lipoidica effectively treated with pentoxifylline.

Abstract
A 30-year-old man had suffered from persistent ulceration within an area of necrobiosis lipoidica diabeticorum for 13 months. The ulcerating necrobiosis lipoidica was resistant to topical therapy and oral therapy with acetylsalicylic acid. However, the ulcers healed completely within 8 weeks of administration of 400 mg pentoxifylline twice daily.
AuthorsK C Noz, M J Korstanje, B J Vermeer
JournalClinical and experimental dermatology (Clin Exp Dermatol) Vol. 18 Issue 1 Pg. 78-9 (Jan 1993) ISSN: 0307-6938 [Print] ENGLAND
PMID8440063 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Pentoxifylline
Topics
  • Administration, Oral
  • Adult
  • Humans
  • Male
  • Necrobiosis Lipoidica (drug therapy)
  • Pentoxifylline (administration & dosage, therapeutic use)
  • Skin Ulcer (drug therapy)

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