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Mebendazole in the treatment of taeniasis solium and taeniasis saginata.

Abstract
A study was made of the effect on taeniasis of mebendazole, a drug known to be highly active against a variety of nematode species parasitic in humans. Thirty-seven patients infected with Taenia solium and four with Taenia saginata, some of whom had concomitant nematode infections, were treated with one of three dosages for 3 to 6 days. Within 48 hours of treatment most patients had eliminated long chains of intact, but apparently lifeless, proglottids. Assessment of results was made by monthly post-treatment observations for 4 to 5 months. The optimum effective dose of mebendazole appears to be 300 mg twice daily for 3 days.
AuthorsA P Chavarria, V M Villarejos, R Zeledón
JournalThe American journal of tropical medicine and hygiene (Am J Trop Med Hyg) Vol. 26 Issue 1 Pg. 118-20 (Jan 1977) ISSN: 0002-9637 [Print] United States
PMID842772 (Publication Type: Journal Article)
Chemical References
  • Benzimidazoles
  • Mebendazole
Topics
  • Adolescent
  • Adult
  • Benzimidazoles (therapeutic use)
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Intestinal Diseases, Parasitic (drug therapy)
  • Male
  • Mebendazole (adverse effects, therapeutic use)
  • Middle Aged
  • Taeniasis (drug therapy)

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