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Superior clinical efficacy of Sinement CR 50/200 versus Sinemet 25/100 in patients with fluctuating Parkinson's disease. An open and a double-blind, double-dummy, multicenter treatment evaluation. Dutch Sinement CR Study Group.

AuthorsE C Wolters, M W Horstink, R A Roos, E N Jansen
JournalAdvances in neurology (Adv Neurol) Vol. 60 Pg. 648-52 ( 1993) ISSN: 0091-3952 [Print] United States
PMID8420204 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)
Chemical References
  • Antiparkinson Agents
  • Drug Combinations
  • carbidopa, levodopa drug combination
  • Levodopa
  • Carbidopa
Topics
  • Antiparkinson Agents (administration & dosage, adverse effects)
  • Carbidopa (administration & dosage, adverse effects)
  • Disability Evaluation
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Drug Administration Schedule
  • Drug Combinations
  • Humans
  • Levodopa (administration & dosage, adverse effects)
  • Movement Disorders (drug therapy)
  • Muscle Rigidity (drug therapy)
  • Neurologic Examination (drug effects)
  • Parkinson Disease (drug therapy)

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