HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Efficacy of (-)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine in African green monkeys infected with simian varicella virus.

Abstract
(-)-9-[4-Hydroxy-2-(hydroxymethyl)butyl]guanine was evaluated for its efficacy in African green monkeys infected with simian varicella virus. Treatment by intramuscular injection was initiated 48 h after virus inoculation and was continued for 10 days; the treatment showed therapeutic effects on rash and viremia at dosages down to 1 mg/kg of body weight per day.
AuthorsK F Soike, R Bohm, J L Huang, B Oberg
JournalAntimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 37 Issue 6 Pg. 1370-2 (Jun 1993) ISSN: 0066-4804 [Print] UNITED STATES
PMID8392312 (Publication Type: Comparative Study, Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Antiviral Agents
  • penciclovir
  • Acyclovir
Topics
  • Acyclovir (analogs & derivatives, pharmacology)
  • Animals
  • Antiviral Agents (pharmacology)
  • Cercopithecus aethiops
  • Dose-Response Relationship, Drug
  • Herpesviridae
  • Herpesviridae Infections (blood, drug therapy)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: