Familial adenomatous polyposis coli and clear cell sarcoma of the kidney.

Abstract

Familial adenomatous polyposis coli is an inherited multiple neoplasia syndrome that is associated with an increased risk for development of another primary tumor. We report a case of a 14-year-old boy who had a proctocolectomy for familial adenomatous polyposis coli. He had survived radical nephrectomy, chemotherapy, and radiotherapy for a congenital clear cell sarcoma of the right kidney. Perhaps the presence of the familial adenomatous polyposis gene induces chromosomal instability in affected persons.

• Authors: I Uzoaru, F J Podbielski, P Chou, J G Raffensperger, F Gonzalez-Crussi
• Journal: Pediatric pathology (Pediatr Pathol) 1993 Mar-Apr Vol. 13 Issue 2 Pg. 133-41 ISSN: 0277-0938 [Print] United States
• PMID: 8385323 (Publication Type: Case Reports, Journal Article)

Topics

• Adenomatous Polyposis Coli (pathology, surgery)
• Adolescent
• Humans
• Kidney Neoplasms (pathology, surgery)
• Male
• Nephrectomy
• Pedigree
• Sarcoma (pathology, surgery)