Efficacy of zeolitic ore compounds on the toxicity of aflatoxin to growing broiler chickens.

Abstract

Commercially available zeolitic ore compounds, when incorporated into the diets at 0.5%, were evaluated for their ability to reduce the deleterious effects of 3.5 mg aflatoxin/kg feed on growing broiler chickens from 1 day to 3 weeks of age. In a series of four experiments, the compounds used included the following: mordenite (particle size of -20 mesh; Zeomite); clinoptilolite (particle size of -20 mesh; Zeobrite); SC Zeolite (particle size of -20 mesh); and clinoptilolite (particle size of -35 mesh; Clino 1) or clinoptilolite (particle sizes of -20 plus +35 mesh; Clino 2). Results demonstrated that 0.5% Zeobrite, Clino 1, or Clino 2 added to aflatoxin-contaminated diets did not significantly (P < 0.05) diminish the toxicity of high concentrations of aflatoxin to growing broiler chicks. Zeomite mordenite ore reduced the toxicity of aflatoxin to growing chicks by 41%, as indicated by weight gains, liver weight, and serum biochemical measurements, which compares favorably with its in vitro binding capacity to aflatoxin. SC Zeolite reduced weight-gain toxicity of aflatoxin by approximately 29%.

• Authors: R B Harvey, L F Kubena, M H Elissalde, T D Phillips
• Journal: Avian diseases (Avian Dis) 1993 Jan-Mar Vol. 37 Issue 1 Pg. 67-73 ISSN: 0005-2086 [Print] United States
• PMID: 8383962 (Publication Type: Journal Article)

Chemical References

• Aflatoxins
• Aluminum Silicates
• mordenite
• Zeolites

Topics

• Adsorption
• Aflatoxins (antagonists & inhibitors, toxicity)
• Aluminum Silicates (pharmacology)
• Animals
• Chickens (growth & development)
• Male
• Particle Size
• Weight Gain (drug effects)
• Zeolites