Abstract |
In a double-blind cross-over trial in 13 patients with exercise-induced asthma, doxantrazole 200 mg taken orally 1 hour before a standardized exercise test involving stair climbing failed to block post-exercise bronchoconstriction. In an open assessment study with the same patients, increasing the doxantrazole dose to 400 mg did not affect post-exercise bronchoconstriction.
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Authors | H Poppius, B Stenius |
Journal | European journal of clinical pharmacology
(Eur J Clin Pharmacol)
Vol. 11
Issue 2
Pg. 107-9
(Jan 03 1977)
ISSN: 0031-6970 [Print] Germany |
PMID | 837962
(Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
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Chemical References |
- Histamine Antagonists
- Tetrazoles
- Thioxanthenes
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Topics |
- Adolescent
- Adult
- Asthma
(drug therapy, etiology, physiopathology)
- Female
- Histamine Antagonists
(therapeutic use)
- Humans
- Male
- Middle Aged
- Peak Expiratory Flow Rate
- Physical Exertion
- Tetrazoles
(therapeutic use)
- Thioxanthenes
(therapeutic use)
- Time Factors
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