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Exercise-induced asthma and doxantrazole.

Abstract
In a double-blind cross-over trial in 13 patients with exercise-induced asthma, doxantrazole 200 mg taken orally 1 hour before a standardized exercise test involving stair climbing failed to block post-exercise bronchoconstriction. In an open assessment study with the same patients, increasing the doxantrazole dose to 400 mg did not affect post-exercise bronchoconstriction.
AuthorsH Poppius, B Stenius
JournalEuropean journal of clinical pharmacology (Eur J Clin Pharmacol) Vol. 11 Issue 2 Pg. 107-9 (Jan 03 1977) ISSN: 0031-6970 [Print] Germany
PMID837962 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article)
Chemical References
  • Histamine Antagonists
  • Tetrazoles
  • Thioxanthenes
Topics
  • Adolescent
  • Adult
  • Asthma (drug therapy, etiology, physiopathology)
  • Female
  • Histamine Antagonists (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Peak Expiratory Flow Rate
  • Physical Exertion
  • Tetrazoles (therapeutic use)
  • Thioxanthenes (therapeutic use)
  • Time Factors

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