[Nephropathy-related disorders of physical and sexual development in girls: experience with successful stimulation by zinc, parlodel and norcolut].

Abstract

The paper reports 3 cases of physical and sexual retardation in girls aged 14-22 with nephropathy: 1 girl had uremia in a conservative stage, 1 patient was put on a chronic hemodialysis for terminal uremia, 1 girl received a renal transplant. In response to combined treatment (zinc sulfate+parlodel) in the former two patients and norcolute therapy in the latter one body mass and growth increased in all the 3. The discussion is concerned with mechanisms of developmental defects in nephropathies, comparative efficacy of the drugs used and social rehabilitation of nephropathy girls with small height and sexual infantilism.

• Authors: A V Kukhtevich, V M Ermolenko, A I Kuznetsova, E P Gitel', A F Bunatian, G A Smirnova, S A Adnoral
• Journal: Terapevticheskii arkhiv (Ter Arkh) Vol. 65 Issue 6 Pg. 54-8 ( 1993) ISSN: 0040-3660 [Print] Russia (Federation)
• Vernacular Title: Sviazannoe s nefropatiiami narushenie fizicheskogo i polovogo razvitiia u devushek: opyt uspeshnoĭ stimuliatsii tsinkom, parlodelom i norkolutom.
• PMID: 8378851 (Publication Type: Case Reports, Comparative Study, English Abstract, Journal Article)

Chemical References

• Bromocriptine
• Zinc
• Norethindrone

Topics

• Adolescent
• Bromocriptine (therapeutic use)
• Combined Modality Therapy
• Female
• Growth Disorders (diagnosis, drug therapy, etiology)
• Humans
• Hypogonadism (drug therapy, etiology)
• Kidney Failure, Chronic (diagnosis, etiology, therapy)
• Kidney Transplantation
• Norethindrone (therapeutic use)
• Renal Dialysis
• Stimulation, Chemical
• Zinc (therapeutic use)