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[Therapeutic effect of hemodialysis on gouty arthritis and tophi in 2 patients with chronic renal failure].

Abstract
Therapeutic effect of hemodialysis on gouty arthritis and tophi in 2 patients with chronic renal failure (CRF) is described. One patient was 74-year-old man with CRF due to benign nephrosclerosis, and had severe secondary gout. There were many tophi in metatarsophalangeal joints of the fingers and toes. Another patient was 44-year-old man with CRF probably due to familial gout. He had many tophi in elbows, knees, wrists, fingers and toes. In both cases initiation of hemodialysis treatment, at first temporally exacerbated gouty arthritis, but thereafter gradually eliminated the tophi. From these results, dialysis treatment is considered to be quite efficient method of treatment for gouty arthritis and tophi in patient with CRF. Gouty arthritis in CRF patient, which does not respond to the conservative therapy, should be considered to be one of the indices for commencement of hemodialysis.
AuthorsO Matsuda, M Otsuka, T Yamada, K Tomita, F Marumo
JournalNihon Jinzo Gakkai shi (Nihon Jinzo Gakkai Shi) Vol. 35 Issue 6 Pg. 783-9 (Jun 1993) ISSN: 0385-2385 [Print] Japan
PMID8377292 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Uric Acid
Topics
  • Adult
  • Aged
  • Arthritis, Gouty (complications, metabolism)
  • Finger Joint (metabolism)
  • Humans
  • Kidney Failure, Chronic (complications, therapy)
  • Male
  • Renal Dialysis
  • Toe Joint (metabolism)
  • Uric Acid (metabolism)

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