[A clinical study on cefditoren pivoxil in pediatrics].

Abstract

Clinical evaluations of cefditoren pivoxil (CDTR-PI, ME 1207) in granules were carried out. The obtained results are summarized as follows. 1. Thirty-nine patients with pediatric infections were treated with CDTR-PI. Clinical responses of 36 assessable cases were excellent in 25, good in 9 and fair in 2. The overall efficacy rate was 94%. 2. Bacteriologically, 30 of the 31 identified bacteria presumed to be pathogens were eradicated and the eradication rate was 97%. 3. Side effects observed were diarrhea in 3 of 39 patients. The incidence was 7.7%. Abnormal laboratory test results were not observed. The results suggested that CDTR-PI might be a very useful and safe drug for the treatment of pediatric infections.

• Authors: Y Satoh, S Iwata, H Akita, T Aoyama, Y Takeuchi, T Yokota, K Sunakawa
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 46 Issue 7 Pg. 596-603 (Jul 1993) ISSN: 0368-2781 [Print] Japan
• PMID: 8371495 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cephalosporins
• cefditoren pivoxil

Topics

• Bacterial Infections (drug therapy, microbiology)
• Cephalosporins (pharmacology, therapeutic use)
• Child
• Child, Preschool
• Female
• Humans
• Infant, Newborn
• Male
• Respiratory Tract Infections (drug therapy)
• Scarlet Fever (drug therapy)
• Urinary Tract Infections (drug therapy)