Leukemic dermal infiltrate at the exit site of a central venous catheter.

Abstract

This report describes the case of a minimally differentiated acute myeloid leukemia (FAB M0) diagnosed in a 55-year-old woman. During a second chemotherapy-induced complete remission, a subcutaneous nodule appeared at the scar of a recently removed Hickman catheter, which when biopsied revealed leukemic infiltration of the dermis and hypodermis. The patient had a bone marrow relapse three weeks later. The authors review similar recent reports and emphasize the importance of recognizing this particular type of cutaneous leukemic relapse.

• Authors: R Martino, A Sureda, D Sitjas, J Nomdedéu, A Domingo-Albòs
• Journal: Haematologica (Haematologica) 1993 Mar-Apr Vol. 78 Issue 2 Pg. 132-4 ISSN: 0390-6078 [Print] Italy
• PMID: 8349191 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Biomarkers, Tumor
• Amsacrine
• Cytarabine
• Etoposide
• Cyclophosphamide
• Prednisolone
• Mitoxantrone
• Vindesine
• Daunorubicin

Topics

• Acute Disease
• Amsacrine (administration & dosage)
• Antineoplastic Combined Chemotherapy Protocols (administration & dosage, therapeutic use)
• Biomarkers, Tumor
• Bone Marrow (pathology)
• Catheterization, Central Venous (adverse effects)
• Cyclophosphamide (administration & dosage)
• Cytarabine (administration & dosage)
• Daunorubicin (administration & dosage)
• Etoposide (administration & dosage)
• Female
• Humans
• Leukemia, Myeloid (drug therapy, pathology)
• Leukemic Infiltration
• Middle Aged
• Mitoxantrone (administration & dosage)
• Neoplasm Seeding
• Prednisolone (administration & dosage)
• Remission Induction
• Salvage Therapy
• Skin (pathology)
• Vindesine (administration & dosage)