Abstract | BACKGROUND: Although malnutrition is frequently associated with diarrhea, most oral rehydration solutions have been tested in well-nourished children. The study tests efficacy of rice, a traditional treatment for diarrhea in Madagascar. PATIENTS AND METHODS: 150 severely malnourished children, aged 6 months to 3 years, took part in this randomized trial. All the children were given oral rehydration solution, (100 ml/kg) in the first 6 hours. The first group (68 children) was given a solution containing glucose, (20 g/l). The second group (82 children) was given a solution containing rice powder (50 g/l). Treatment was then continued according to WHO recommendations, including feeding after rehydration (mixture of milk, oil and sugar). RESULTS: The age, weight, height, duration of diarrhea before admission, degree of dehydration and pathogens in stools of the two groups were comparable on admission. Only 2 patients were withdrawn from the trial. The percentage of death was the same in both groups: 16% of those given glucose and 15% of those given rice-based rehydration solution. The weight gains were similar in both groups; the duration of diarrhea was 89 +/- 6 hours in the glucose-fed groups and 68 +/- 4 hours for those given the rice-based rehydration solution (p < 0.02). CONCLUSIONS:
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Authors | O Razafindrakoto, N Ravelomanana, F Randriamiharisoa, V Rasoarivao, V Ramialimanana, D R Rakotoarimanana, M Razanamparany |
Journal | Archives francaises de pediatrie
(Arch Fr Pediatr)
Vol. 50
Issue 2
Pg. 101-5
(Feb 1993)
ISSN: 0003-9764 [Print] France |
Vernacular Title | La solution de réhydratation orale (SRO) à base de riz, alternative de la SRO de l'OMS dans la diarrhée aiguë des malnutris. |
PMID | 8343013
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Acute Disease
- Child Nutrition Disorders
(complications)
- Child, Preschool
- Diarrhea, Infantile
(complications, therapy)
- Female
- Fluid Therapy
- Humans
- Infant
- Infant Nutrition Disorders
(complications)
- Male
- Nutrition Disorders
(therapy)
- Oryza
- Rehydration Solutions
(therapeutic use)
- World Health Organization
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