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[Oral rice-based rehydration solution (SRO), alternative of SRO of WHO in acute diarrhea in malnourished patients].

AbstractBACKGROUND:
Although malnutrition is frequently associated with diarrhea, most oral rehydration solutions have been tested in well-nourished children. The study tests efficacy of rice, a traditional treatment for diarrhea in Madagascar.
PATIENTS AND METHODS:
150 severely malnourished children, aged 6 months to 3 years, took part in this randomized trial. All the children were given oral rehydration solution, (100 ml/kg) in the first 6 hours. The first group (68 children) was given a solution containing glucose, (20 g/l). The second group (82 children) was given a solution containing rice powder (50 g/l). Treatment was then continued according to WHO recommendations, including feeding after rehydration (mixture of milk, oil and sugar).
RESULTS:
The age, weight, height, duration of diarrhea before admission, degree of dehydration and pathogens in stools of the two groups were comparable on admission. Only 2 patients were withdrawn from the trial. The percentage of death was the same in both groups: 16% of those given glucose and 15% of those given rice-based rehydration solution. The weight gains were similar in both groups; the duration of diarrhea was 89 +/- 6 hours in the glucose-fed groups and 68 +/- 4 hours for those given the rice-based rehydration solution (p < 0.02).
CONCLUSIONS:
Both glucose and rice-based rehydration solutions are equally effective for rehydrating severely malnourished children with acute diarrhea. The rice-based rehydration solution also reduces the duration of diarrhea.
AuthorsO Razafindrakoto, N Ravelomanana, F Randriamiharisoa, V Rasoarivao, V Ramialimanana, D R Rakotoarimanana, M Razanamparany
JournalArchives francaises de pediatrie (Arch Fr Pediatr) Vol. 50 Issue 2 Pg. 101-5 (Feb 1993) ISSN: 0003-9764 [Print] France
Vernacular TitleLa solution de réhydratation orale (SRO) à base de riz, alternative de la SRO de l'OMS dans la diarrhée aiguë des malnutris.
PMID8343013 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
Chemical References
  • Rehydration Solutions
Topics
  • Acute Disease
  • Child Nutrition Disorders (complications)
  • Child, Preschool
  • Diarrhea, Infantile (complications, therapy)
  • Female
  • Fluid Therapy
  • Humans
  • Infant
  • Infant Nutrition Disorders (complications)
  • Male
  • Nutrition Disorders (therapy)
  • Oryza
  • Rehydration Solutions (therapeutic use)
  • World Health Organization

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