Is Tolosa-Hunt syndrome a limited form of Wegener's granulomatosis? Report of two cases with anti-neutrophil cytoplasmic antibodies.

Abstract

Two patients with recurrent painful ophthalmoplegia due to granulomatous involvement of the intracavernous sinus (Tolosa-Hunt syndrome) had circulating anti-neutrophil cytoplasmic antibodies with a granular cytoplasmic immunofluorescence pattern during a flare-up of the disease. The presence of these antibodies suggests that Tolosa-Hunt syndrome might be regarded as a localized form of Wegener's granulomatosis.

• Authors: C Montecucco, R Caporali, C Pacchetti, M Turla
• Journal: British journal of rheumatology (Br J Rheumatol) Vol. 32 Issue 7 Pg. 640-1 (Jul 1993) ISSN: 0263-7103 [Print] England
• PMID: 8339143 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Antineutrophil Cytoplasmic
• Autoantibodies

Topics

• Adult
• Antibodies, Antineutrophil Cytoplasmic
• Autoantibodies (analysis, immunology)
• Female
• Fluorescent Antibody Technique
• Granulomatosis with Polyangiitis (complications, diagnosis, immunology)
• Humans
• Middle Aged
• Ophthalmoplegia (diagnosis, etiology, immunology)