Renal transplantation in leprosy patients.

Abstract

We report four cases of leprosy in renal transplant recipients, two of whom had the disease before transplantation and no signs of relapse even in the presence of immunosuppressive drugs. The other two cases presented with lepromatous and borderline (dimorphous) leprosy 5 months and 5 years after transplantation, respectively. The disease of the last patient was controlled with sulfone even in the presence of immunosuppressive drugs, but the mechanism whereby the first patient rapidly developed lepromatous leprosy is unclear, even though he was a home contact of a patient with lepromatous leprosy (his wife). In view of the data presented here, we do not contraindicate renal transplantation in patients with leprosy who frequently suffer changes in renal function. We believe that renal function should be periodically evaluated in patients with borderline and lepromatous leprosy.

• Authors: A M Roselino, A M de Almeida, N T Foss, V J Lima, E O Raspanti, A S Ferraz
• Journal: International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association (Int J Lepr Other Mycobact Dis) Vol. 61 Issue 1 Pg. 102-5 (Mar 1993) ISSN: 0148-916X [Print] United States
• PMID: 8326170 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Female
• Humans
• Kidney Failure, Chronic (complications, surgery)
• Kidney Transplantation
• Leprosy (complications)
• Leprosy, Borderline (complications)
• Leprosy, Lepromatous (complications)
• Male
• Middle Aged
• Postoperative Complications