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Defective galactosylation and clearance of IgA1 molecules as a possible etiopathogenic factor in IgA nephropathy.

AuthorsJ Mestecky, M Tomana, P A Crowley-Nowick, Z Moldoveanu, B A Julian, S Jackson
JournalContributions to nephrology (Contrib Nephrol) Vol. 104 Pg. 172-82 ( 1993) ISSN: 0302-5144 [Print] Switzerland
PMID8325028 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Carbohydrates
  • Immunoglobulin A
  • Immunoglobulin Heavy Chains
  • Lectins
  • Plant Lectins
  • jacalin
  • Galactose
Topics
  • Amino Acid Sequence
  • Animals
  • Carbohydrate Sequence
  • Carbohydrates (physiology)
  • Galactose (metabolism)
  • Glomerulonephritis, IGA (etiology, immunology, metabolism)
  • Glycosylation
  • Humans
  • Immunoglobulin A (chemistry, metabolism)
  • Immunoglobulin Heavy Chains (chemistry)
  • Lectins (metabolism)
  • Liver (metabolism)
  • Mice (metabolism)
  • Molecular Sequence Data
  • Plant Lectins
  • Primates (metabolism)
  • Protein Processing, Post-Translational

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