Abstract |
It is estimated that approximately 2 percent of African-Americans possess one gene for C hemoglobin. This is usually demonstrated on hemoglobin electrophoresis. Hemoglobin C trait (AC hemoglobinopathy) is considered a clinically benign condition; there are no characteristic physical abnormalities. Angioid streaks in the ocular fundus represent a progressive, bilateral, degenerative disorder characterized by breaks in Bruch's membrane. The pathogenesis of angioid streaks in the hemoglobinopathies is thought to be linked to iron deposition in Bruch's membrane. This report describes what is believed to be the first reported case of angioid streaks associated with hemoglobin C trait.
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Authors | G M McBrayer, L Semes, G G Stephens |
Journal | Journal of the American Optometric Association
(J Am Optom Assoc)
Vol. 64
Issue 4
Pg. 250-3
(Apr 1993)
ISSN: 0003-0244 [Print] United States |
PMID | 8315200
(Publication Type: Case Reports, Journal Article)
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Topics |
- Angioid Streaks
(complications)
- Hemoglobin C Disease
(complications)
- Humans
- Male
- Middle Aged
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