[Detection of human papillomavirus DNA and clinicopathological study of vulvar human papillomavirus infection].

Abstract

We studied 217 vulvar HPV infection patients by clinically, pathologically, and virologically. From 90.6% of the cauliflower-like vulvar lesions and 29.7% of the papillomatous and finger-like lesions, we detected HPV 6/11 DNA by dot blotting hybridization. The patients in 90.0% of the cauliflower-like group and 9.8% of the papillomatous and finger-like group had a high risk factor to intercourse with different sex partners (P < 0.0001). The pathological characteristics, nature history, and response to treatment were different. According to clinical, pathological, and virological findings divided three types: vulvar HPV infection type 1 (or condylomata acuminata), vulvar HPV infection type 2, and vulvar HPV infection type 3.

• Authors: S R Fan
• Journal: Zhonghua yi xue za zhi (Zhonghua Yi Xue Za Zhi) Vol. 73 Issue 10 Pg. 590-2, 636-7 (Oct 1993) ISSN: 0376-2491 [Print] China
• PMID: 8313179 (Publication Type: English Abstract, Journal Article)

Chemical References

• DNA, Viral

Topics

• Adult
• DNA, Viral (analysis)
• Female
• Humans
• Middle Aged
• Papillomaviridae (genetics, isolation & purification)
• Papillomavirus Infections (microbiology, pathology)
• Tumor Virus Infections (microbiology, pathology)
• Vulvitis (microbiology, pathology)