[Local immunity indices during the chigain treatment of chronic cystitis in children].

Abstract

A total of 117 children with chronic pyelonephritis (CP) aged 4-14 were examined and treated. 57 of them having attendant cystitis received multimodality treatment comprising local intravesicular instillations of chigain controlled by clinical findings, urinalysis, cystoscopy and urinary secretory immunoglobulins SIg A1, SIg A2 and IgG. The drug chigain capable of immune replacement was found to initiate clinical response, positive trends in urinalysis and cystoscopy data, in the levels of secretory urine immunoglobulins. The findings show the need of immune replacement therapy in the complex of modalities to treat children with CP combined with cystitis.

• Authors: P K Iatsyk, V V Botvin'eva, T B Sentsova, A T Tadzhibaev, Iu M Akhmedov, S N Zorkin, K M Madibraimov
• Journal: Urologiia i nefrologiia (Urol Nefrol (Mosk)) 1993 Sep-Oct Issue 5 Pg. 13-5 ISSN: 0042-1154 [Print] Russia (Federation)
• Vernacular Title: Pokazateli mestnogo immuniteta pri lechenii khronicheskogo tsistita u deteĭ chigainom.
• PMID: 8310575 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Biological Factors
• Immunoglobulins
• chigain

Topics

• Adolescent
• Biological Factors (therapeutic use)
• Child
• Child, Preschool
• Chronic Disease
• Colostrum
• Cystitis (complications, immunology, therapy)
• Drug Evaluation
• Female
• Humans
• Immunoglobulins (drug effects, urine)
• Infant
• Pregnancy
• Pyelonephritis (etiology, immunology, therapy)