[A study on P21(ras) in human lung cancer and body fluid of cancer patients].

Abstract

The McAb of anti-P21(ras) has been used to screen 9 cases of human lung cancer tissues, 18 cases of samples and 2 cases of hydrothorax samples of lung cancer patients by means of PAGE-immunoblots. The expression of ras gene was found in 8 cases of human lung cancer among which the expression of 4 cases was higher than that of normal control. P21(ras) has not been detected in serum and hydrothorax samples of cancer patients. The present study indicated that there was P21(ras) in human lung cancer and normal control and the expression level of ras gene in lung cancer was related to the differentiation of cancer.

• Authors: X Lin, X Shu, Z Sun, J Zhao, Z Sun
• Journal: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao (Hua Xi Yi Ke Da Xue Xue Bao) Vol. 24 Issue 3 Pg. 233-6 (Sep 1993) ISSN: 0257-7712 [Print] China
• PMID: 8288186 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• HRAS protein, human
• Proto-Oncogene Proteins p21(ras)

Topics

• Adenocarcinoma (genetics, metabolism)
• Carcinoma, Squamous Cell (genetics, metabolism)
• Exudates and Transudates (metabolism)
• Gene Expression
• Genes, ras
• Humans
• Lung Neoplasms (genetics, metabolism)
• Proto-Oncogene Proteins p21(ras) (biosynthesis)