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Bilateral vocal cord paralysis secondary to treatment of severe hypophosphatemia in a continuous ambulatory peritoneal dialysis patient.

Abstract
Neuromuscular complications, including tetany and laryngeal spasm, are recognized complications of hypocalcemia and hypomagnesemia. We present a continuous ambulatory peritoneal dialysis patient with hypomagnesemia who developed hyperphosphatemia and profound hypocalcemia after oral phosphate replacement for severe hypophosphatemia. The combination of hypocalcemia and hypomagnesemia resulted in life-threatening bilateral vocal cord paralysis. Phosphate replacement should be determined and given cautiously, particularly in patients with renal failure and concomitant electrolyte disturbances.
AuthorsW C Lye, S O Leong
JournalAmerican journal of kidney diseases : the official journal of the National Kidney Foundation (Am J Kidney Dis) Vol. 23 Issue 1 Pg. 127-9 (Jan 1994) ISSN: 0272-6386 [Print] United States
PMID8285187 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Magnesium
Topics
  • Female
  • Humans
  • Hypocalcemia (chemically induced, complications)
  • Hypophosphatemia (drug therapy, etiology)
  • Magnesium (blood)
  • Middle Aged
  • Peritoneal Dialysis, Continuous Ambulatory (adverse effects)
  • Tetany (etiology)
  • Vocal Cord Paralysis (etiology)

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