Recombinant interferon-alpha efficacy in relapsed adult nephroblastoma: a case report.

Abstract

We report on a 37-year-old woman with progressive lung and pleural metastases from a right nephroblastoma, who achieved partial remission with recombinant interferon-alpha. The drug was given subcutaneously at a dose of 5 mu. 3 times per week. The response was documented after 3 months of treatment and was maintained for at least 9 months. Although such a response has not been reported in the literature, this case suggests promising activity of recombinant interferon-alpha in relapsed nephroblastoma.

• Authors: J Kattan, J P Droz, S Culine, B Escudier, C Beaumont-Raymond
• Journal: The Journal of urology (J Urol) Vol. 151 Issue 2 Pg. 411-2 (Feb 1994) ISSN: 0022-5347 [Print] United States
• PMID: 8283539 (Publication Type: Case Reports, Journal Article)

Chemical References

• Interferon-alpha
• Recombinant Proteins

Topics

• Adult
• Female
• Humans
• Interferon-alpha (therapeutic use)
• Kidney Neoplasms (pathology, therapy)
• Lung Neoplasms (secondary, therapy)
• Neoplasm Recurrence, Local (therapy)
• Pleural Neoplasms (secondary, therapy)
• Recombinant Proteins (therapeutic use)
• Remission Induction
• Wilms Tumor (secondary, therapy)