SHORT syndrome and insulin resistance.

Abstract

We describe a further case of SHORT syndrome. This girl shows nearly all the typical manifestations reported in patients with SHORT syndrome. However, at 14 years she presented with non-ketotic hyperglycemia. At 16 1/2 years, the diagnosis of diabetes mellitus secondary to severe insulin resistance was made by intravenous insulin challenge. Insulin resistant diabetes mellitus seems to be a new finding in SHORT syndrome, not previously described in this condition.

• Authors: J Schwingshandl, C J Mache, K Rath, M H Borkenstein
• Journal: American journal of medical genetics (Am J Med Genet) Vol. 47 Issue 6 Pg. 907-9 (Nov 01 1993) ISSN: 0148-7299 [Print] United States
• PMID: 8279490 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Abnormalities, Multiple (physiopathology)
• Adolescent
• Body Height
• Female
• Humans
• Insulin Resistance
• Male
• Syndrome