The effect of aluminum hydroxide dissolution on the bleeding of aluminum lake dyes.

Abstract

The effect of pH on the bleeding of FD&C yellow No. 5 aluminum lake and FD&C red No. 40 aluminum lake was investigated. The pH-bleeding profiles corresponded to the pH-solubility profile of aluminum hydroxide. The similarity of the bleeding profiles of both lake dyes and the pH-solubility profile of aluminum hydroxide indicates that pH related bleeding, other than that occurring by competition with anions, is a result of dissolution of the aluminum hydroxide substrate. This dissolution is related to the properties of the substrate rather than to the structure of adsorbed dye.

• Authors: A Desai, G E Peck, J E Lovell, J L White, S L Hem
• Journal: Pharmaceutical research (Pharm Res) Vol. 10 Issue 10 Pg. 1458-60 (Oct 1993) ISSN: 0724-8741 [Print] United States
• PMID: 8272407 (Publication Type: Journal Article)

Chemical References

• Azo Compounds
• Coloring Agents
• Allura Red AC Dye
• Aluminum Hydroxide
• Tartrazine

Topics

• Aluminum Hydroxide (chemistry)
• Azo Compounds (chemistry)
• Coloring Agents (chemistry)
• Hydrogen-Ion Concentration
• Solubility
• Tartrazine (chemistry)