| Abstract | The authors report on the case of a 32 year old woman treated with prednisone and diphenylsulfon for a multi-visceral sarcoidosis; headache and progressive oculomotor paralysis revealed an expansive lesion of the left cavernous sinus extending to the temporal fossa. C.T. scan, M.R.I., and angiographic data as well as the intra-operative findings evoked the diagnosis of meningioma. Pathological findings showed an epithelioid and gigantocellular granuloma without caseous necrosis, corresponding to a sarcoidosic lesion. After the operation, the increase of steroid doses was followed by a complete regression of the tumoral remnants, and total clinical recovery. In a patient having a previously diagnosed sarcoidosis with evidence of an intracranial tumor mimicking a meningioma, steroids should be first prescribed. Efficacy of steroids on sarcoid granulomas is often dramatic; surgical approach would be discussed in case of ineffective steroid therapy, of persisting questionnable diagnosis, and of tumoral threatening compression. |
| Authors | F Nataf, B Devaux, C Lamy, C Fallet-Bianco, F X Roux
(Affiliation: Service de Neurochirurgie, Centre Hospitalier Ste Anne, Paris.)
|
| Journal | Neuro-Chirurgie
(Neurochirurgie)
Vol. 39
Issue 2
Pg. 128-31
( 1993)
ISSN: 0028-3770 FRANCE |
| Vernacular Title | Localisation sphéno-caverneuse de la neurosarcoïdose méningée. A propos d'un cas et revue de la littérature. |
| PMID | 8247216
(Publication Type: Case Reports, English Abstract, Journal Article, Review)
|
| Chemical References |
|
| Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Cavernous Sinus
- Central Nervous System Diseases
(etiology, pathology, radiography)
- Diagnosis, Differential
- Female
- Humans
- Meningeal Neoplasms
(diagnosis)
- Meninges
(pathology, radiography)
- Meningioma
(diagnosis)
- Sarcoidosis
(complications, drug therapy, pathology)
- Tomography, X-Ray Computed
|
