[Efficacy and tolerance of a local application of phenazone and chlorhydrate lidocaine (Otipax) in infants and children with congestive otitis].

Abstract

The efficacy and safety of ear drops containing phenazone and lidocaine hydrochloride (Otipax) for the treatment of congestive myringitis were evaluated in 18 infants and children aged 1 to 10 years. Relief of pain was evident 5 minutes after instillation and significant after 15 to 30 minutes. Serial photographs of the tympanic membrane demonstrated prompt improvement of inflammation. Congestion was significantly reduced after five minutes and overall ear drum color was significantly improved after 15 to 30 minutes. No adverse effects were recorded. These data suggest that Otipax is effective and safe for the treatment of painful congestive myringitis in infants and children.

• Authors: M François
• Journal: Annales de pediatrie (Ann Pediatr (Paris)) Vol. 40 Issue 7 Pg. 481-4 (Sep 1993) ISSN: 0066-2097 [Print] France
• Vernacular Title: Efficacité et tolérance d'une application locale de phénazone et de chlorhydrate de lidocaïne (Otipax) dans les otites congestives du nourrisson et de l'enfant.
• PMID: 8239401 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Drug Combinations
• Otipax
• Aminopyrine
• Lidocaine

Topics

• Aminopyrine (administration & dosage, therapeutic use)
• Child
• Child, Preschool
• Drug Combinations
• Earache (diagnosis, etiology)
• Humans
• Infant
• Instillation, Drug
• Lidocaine (administration & dosage, therapeutic use)
• Otitis Media with Effusion (complications, diagnosis, drug therapy, pathology)
• Pain Measurement
• Severity of Illness Index