Intracranial plasma cell granuloma presenting as an optic neuropathy.

Abstract

A 40-year-old man presented with a left optic neuropathy. Magnetic resonance imaging demonstrated a contrast-enhancing mass along the course of the left trigeminal nerve and in the region of the left cavernous sinus with suprasellar extension. Preoperatively, he had a serum polyclonal gammopathy. Pathologic diagnosis was an intracranial plasma cell granuloma. The patient responded to high-dose steroids with resolution of his optic neuropathy, marked decrease in the size of the mass, and resolution of the serum polyclonal gammopathy. Intracranial plasma cell granuloma is a rare lesion; only 11 cases have been described in the literature. Almost half of the patients presented with vision loss as their chief complaint.

• Authors: S R Kodsi, B R Younge, J A Leavitt, R J Campbell, B W Scheithauer
• Journal: Survey of ophthalmology (Surv Ophthalmol) 1993 Jul-Aug Vol. 38 Issue 1 Pg. 70-4 ISSN: 0039-6257 [Print] United States
• PMID: 8235996 (Publication Type: Case Reports, Journal Article)

Chemical References

• Prednisone

Topics

• Adult
• Brain Diseases (diagnosis, drug therapy, surgery)
• Diagnosis, Differential
• Granuloma, Plasma Cell (diagnosis, drug therapy, surgery)
• Humans
• Magnetic Resonance Imaging
• Male
• Optic Nerve Diseases (diagnosis, drug therapy)
• Prednisone (therapeutic use)
• Trigeminal Nerve (pathology)