Myelography, CT and MRI in leukaemic infiltration of the lumbar theca.

Abstract

A 25-year-old woman with acute lymphoblastic leukaemia, while in remission, developed paraparesis, with faecal and urinary incontinence. CT demonstrated increased density of the lumbar theca and enlargement of the nerve roots. Myelography showed complete obstruction below the L3 level. MRI showed increased signal intensity in the lumbar sac on T1 weighting, and the cauda equina enhanced with gadolinium-DTPA. Lymphoblasts were seen in the lumbar spinal fluid. After chemotherapy, these abnormalities resolved, as did the paraparesis and incontinence.

• Authors: W C Shen, S K Lee, Y J Ho, K R Lee
• Journal: Neuroradiology (Neuroradiology) Vol. 35 Issue 7 Pg. 516-7 ( 1993) ISSN: 0028-3940 [Print] Germany
• PMID: 8232878 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Combined Modality Therapy
• Female
• Humans
• Leukemic Infiltration (diagnosis, drug therapy, pathology, radiotherapy)
• Lumbar Vertebrae (pathology)
• Magnetic Resonance Imaging
• Myelography
• Neurologic Examination (drug effects, radiation effects)
• Precursor Cell Lymphoblastic Leukemia-Lymphoma (pathology)
• Spinal Nerve Roots (pathology)
• Subarachnoid Space (pathology)
• Tomography, X-Ray Computed