[A case of postoperative chylothorax successfully treated by chemical pleurodesis with OK-432].

Abstract

Recently, cases of postoperative chylothorax have increased concomitantly with the increase in number of aggressive thoracic surgery. Chylothorax was complicated on the 6 th postoperative day in a 69-year-old male who underwent right lower lobectomy with mediastinal lymph node dissection for adenocarcinoma of the lung. After the leaking point from thoracic duct was confirmed by lymphangiography and chest CT, OK-432 1.5 KE was instilled into the intrapleural space through a intrathoracic tube. By this procedure, the chylous fistulas were completely cured. Application of OK-432, even in such a small dose as 1.5 KE, appeared very useful for the treatment of postoperative chylothorax.

• Authors: H Matsumoto, N Mitani, H Ogawa, Y Horikawa, H Nishijima, T Shimotakahara, H Shimazu, T Oyama
• Journal: Kyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 46 Issue 11 Pg. 987-9 (Oct 1993) ISSN: 0021-5252 [Print] Japan
• PMID: 8230920 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Picibanil

Topics

• Adenocarcinoma (surgery)
• Aged
• Chylothorax (etiology, therapy)
• Humans
• Instillation, Drug
• Lung Neoplasms (surgery)
• Male
• Picibanil (administration & dosage, therapeutic use)
• Pleura
• Pneumonectomy (adverse effects)