HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Recurrent venous thromboses in hypoplasia of the vena cava inferior and factor XII deficiency].

Abstract
The cause of recurrent pelvic and leg venous thromboses in a 24-year-old man was found to be a combination of two rare anomalies, hypoplasia of the hepatic, prerenal segment of the inferior vena cava and factor XII deficiency (factor XII activity 38%, its antigen 39% of normal), the latter considered a risk factor for thromboembolism. Subsequent fibrinolysis was not successful. No thromboembolic phenomena occurred during the following 16 months of oral anticoagulation with phenprocoumon. When this treatment was discontinued at the patient's behest, there was a recurrence on the contralateral side. Anticoagulation was resumed and has continued now for 1 1/2 years without recurrence. The patient has been largely free of symptoms. Permanent anticoagulation thus seems unavoidable in this case.
AuthorsW M Halbmayer, J Radek, P Duschet, G Lindeck, F Gschnait, H Czembirek, M Fischer
JournalDeutsche medizinische Wochenschrift (1946) (Dtsch Med Wochenschr) Vol. 118 Issue 43 Pg. 1561-6 (Oct 29 1993) ISSN: 0012-0472 [Print] Germany
Vernacular TitleRezidivierende Venenthrombosen bei Vena-cava-inferior-Hypoplasie und Faktor-XII-Mangel.
PMID8223205 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Factor XII
Topics
  • Adult
  • Diagnosis, Differential
  • Drug Therapy, Combination
  • Factor XII (analysis)
  • Factor XII Deficiency (complications, diagnosis, drug therapy)
  • Humans
  • Male
  • Radiography
  • Recurrence
  • Thrombolytic Therapy
  • Thrombophlebitis (diagnosis, drug therapy, etiology)
  • Ultrasonography
  • Vena Cava, Inferior (abnormalities, diagnostic imaging)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: