Should osteoarthritis be treated with nonsteroidal anti-inflammatory drugs?

Abstract

Numerous studies have demonstrated the efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) and their superiority to placebo as symptomatic treatment for osteoarthritis (OA). Unquestionably, use of NSAIDs has reduced joint pain and improved mobility for millions of patients with OA. This article explores the uncertainty that exists regarding the use of NSAIDs in the treatment of OA.

• Authors: K D Brandt
• Journal: Rheumatic diseases clinics of North America (Rheum Dis Clin North Am) Vol. 19 Issue 3 Pg. 697-712 (Aug 1993) ISSN: 0889-857X [Print] United States
• PMID: 8210582 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S., Review)

Chemical References

• Analgesics
• Anti-Inflammatory Agents, Non-Steroidal
• Acetaminophen

Topics

• Acetaminophen (adverse effects, economics, therapeutic use)
• Analgesics (therapeutic use)
• Anti-Inflammatory Agents, Non-Steroidal (adverse effects, economics, therapeutic use)
• Cartilage, Articular (pathology)
• Drug Costs
• Humans
• Joints (physiopathology)
• Osteoarthritis (drug therapy, pathology, physiopathology)
• Pain
• Synovitis (physiopathology)