A case report of drug-induced allergic hepatitis probably due to the N-methyltetrazolethiol group cephalosporin.

Abstract	Drug-induced allergic hepatitis occurred in a patient being treated with cefpiramide sodium. A lymphocyte blast transformation test suggested that the N-methyltetrazolethiol group of the drug was responsible for the induction of acute hepatitis. A detailed case report and discussion of the relevant literature are presented in this paper.
Authors	N Kojima, I Kumamoto, T Masumoto, M Onji
Journal	Arerugi = [Allergy] (Arerugi) Vol. 43 Issue 3 Pg. 511-4 (Mar 1994) ISSN: 0021-4884 [Print] Japan
PMID	8198460 (Publication Type: Case Reports, Journal Article)
Chemical References	Cephalosporins cefpiramide
Topics	Acute Disease Adult Cephalosporins (adverse effects) Chemical and Drug Induced Liver Injury (etiology, immunology) Drug Hypersensitivity (etiology, immunology) Female Humans Lymphocyte Activation (drug effects)

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