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Laparoscopic bilateral nephrectomy for renin-mediated hypertension.

Abstract
Hypertension arising from retained native kidneys complicates the management of recipients of renal transplants. Reluctance to administer angiotensin-converting enzyme inhibitor (ACEI) drugs to patients taking cyclosporine has reopened the question of performing native nephrectomies for poorly controlled, renin-dependent hypertension. We report the first published cases of simultaneous bilateral laparoscopic nephrectomies in 2 patients: 1 in preparation for living-related donor transplantation and the other ten months following cadaver transplantation in a patient whose end-stage renal disease was from malignant nephrosclerosis. Both had very severe hypertension resistant to multiple drugs and both became normotensive with little or no antihypertensive medication following nephrectomies. A bilateral nephrectomy is currently feasible using a laparoscopic approach.
AuthorsG T Bales, S K Fellner, G W Chodak, D B Rukstalis
JournalUrology (Urology) Vol. 43 Issue 6 Pg. 874-7 (Jun 1994) ISSN: 0090-4295 [Print] United States
PMID8197654 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Renin
Topics
  • Adult
  • Female
  • Humans
  • Hypertension (etiology, prevention & control, surgery)
  • Kidney Transplantation
  • Laparoscopy (methods)
  • Male
  • Middle Aged
  • Nephrectomy (methods)
  • Postoperative Complications (etiology, prevention & control, surgery)
  • Preoperative Care
  • Renin (physiology)

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