[2,8 dihydroxyadenine(2,8 DHA) lithiasis. Report of 3 cases].

Abstract

Presentation of three cases of 2,8 dihydroxyadenine calculi. This is an infrequent but potentially serious form of lithiasis, of purinic origin, caused by a genetic abnormality (deficit of adenine phosphoribosyltransferase, APRT) affecting both sexes. Frequent confusion of this form with uric lithiasis forces to try the use of IR spectrum or X-ray diffraction. Long-term follow-up of these patients and treatment with allopurinol, avoiding alkalinizating agents, is essential.

• Authors: O Wuhl, R Vila, P Barcelo, P Laguna, A Rousaud
• Journal: Actas urologicas espanolas (Actas Urol Esp) Vol. 18 Issue 1 Pg. 43-6 (Jan 1994) ISSN: 0210-4806 [Print] Spain
• Vernacular Title: Litiasis de 2,8 dihidroxiadenina (2,8 DHA). A próposito de tres casos.
• PMID: 8191945 (Publication Type: Case Reports, English Abstract, Journal Article, Review)

Chemical References

• Purines
• 2,8-dihydroxyadenine
• Adenine

Topics

• Adenine (analogs & derivatives, analysis)
• Adult
• Diagnosis, Differential
• Female
• Humans
• Male
• Purines (metabolism)
• Urinary Calculi (chemistry, diagnosis, etiology, genetics, metabolism, therapy)